From Lexington:  Take Interstate 75 south to exit 141 (Hwy 63).  Turn right on Hwy 63 and go until it dead ends into Hwy 27 north.  Turn right onto 27 north.  At the first light, turn left (Hwy 297).  Go to the stop sign and turn left (still Hwy 297).  At the Terry & Terry store, turn left onto Leatherwood Ford Rd. (297).  Go 13.5 miles through the park.  True West will be on your right.

Alternate Route for very large trailers coming from the east (to avoid driving through the "gorge" in the park):  From Interstate 75, get off at exit 141 and head west on Hwy 63.  Turn left on Hwy 27 south to Elgin.  Turn right on Hwy 52 to Allardt.  Turn right at the 4-way stop sign to go north on Hwy 127.  Turn right on Hwy 154.  Go approximately 8-10 miles and turn right on 297 (Leatherwood Ford Rd.).  True West is 4.5 miles down on the left.